Edited by: 
 Philip Lazarovici, Micha E. Spira, Eliahu Zlotkin; 
 The Interuniversity Institute for Marine Sciences, Eilat (IUI)

 1996, 232 pages, $84.00, Hard Cover, ISBN 1-880293-07-02

In a meeting held at "The Inter-university Institute for Marine Sciences, Eilat" (IUI), a group of experts gathered to discuss recent developments in the understanding of the structure, biochemistry, molecular biology, function and potential use of bioactive materials from marine organisms. The articles presented in this book reveal the "broad and unpredictable spectrum of molecular architecture which one encounters" in marine organisms as stated by Dr. Scheuer.

TABLE OF CONTENTS:
Marine Metabolites as Drug Leads - Retrospect and Prospect, P.J.Scheuer; 
Conus Venom Peptides (Conopeptides): Inter-Species, Intra-Species and Within Individual
          Variation Revealed by Ionspray Mass Spectrometry, J-P. Bingham, A. Jones,
          R. J. Lewis, P. R. Andrews and P. F. Alewood;
a-Conotoxins and Nicotinic Acetylcholine Receptors, J. M. McIntosh; 
Novel Hydrophobic w-Conotoxins from Molluscivorous Conus Venoms, M. Fainzibler, 
          J. C. Lodder, R. van der Schors, K. W. Li, W. P. M. Geraerts and K. S. Kits;
The o-Conotoxins Inhibit Sodium Current Inactivation Through Binding To Distinct But
          Related Receptor Sites On Sodium Channels, D. Gordon, E. Zlotkin, O. Kofman,
          K. S. Kits and M. Fainzilber;
Electrophysiological Analysis of Target Strategies of Molluscivorous Cone Snail
          Neurotoxins, M. E. Spira, A. Hasson and R. Oren;
Functional Diversity of a Venom Polypeptide in Marine Ecosystems, E. Zlotkin, 
          I. Napchi-Shichor, D. Gordon and M. Fainzilber;
Sea Anemone Toxins Affecting Sodium Channels: Are the Similarities Greater Than 
          the Differences?, W. R. Kem, M. W. Pennington, D. S. Krafte and R. J. Hill;
Potassium Channel Neurotoxins from Sea Anemones, A. L. Harvey, E. G. Rowan,
          H. Vatanpour, L. C. Young, O. Castaneda, D. Mebs, C. Cervenansky and 
          E. Karlsson;
Toxinology and Ecology of the Mediterranean Jellyfish Rhopilema nomadica,
          A. Lotan, L. Fishman, R. B. Hillel, Y. Loya and E. Zlotkin;
Sea Snake Postsynaptic Neurotoxins: Structure-Function Relationship and 
          Interaction With Acetylcholine Receptor, A. T. Tu;
The Role of Calcium, Protein Kinase C, Pertussis Toxin Substrates and Eicosanoids
          on Pardaxin Induced Dopamine Release from PC12 Pheochromocytoma
          Cells, E. Shilderman-Bloch, S. Abu-Raya, D. Rasouly, O. Furman, V. Trumbovler,
          D. Shavit, P. I. Lelkes, E. Shohami, Y. Gutman, and P. Lazarovici;
Mechanism of Membrane Permeation: Pore Formation by the Shark Repellent Neuerotoxin
          Pardaxin, Versus Membrane Disruption by Antibacterial Polypeptides, Y. Shai;
Antiviral and Anticoagulant Activity of Polysaccharides from Marine Brown Algae,
          T. Bruhn, J. Durig, E. N. Kraiselburd, E. De Clercq, H-D. Bruhn, and L. Beress;
Bioactive Sponge and Ascidian Secondary Metabolites, Y. Kashman and A. Rudi